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Last year I had everyone at my family reunion sign a piece of fabric. I put them all together in a Rail Fence quilt and took it to this year's reunion for the Chinese auction.
I hand basted it using Sharon Schamber's method. (I recommend it highly, she has made a painful process so much easier.) I quilted it on my DSM.
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The back was pieced with large squares, an idea I got from Bonnie Hunter at Quiltville. I really like the look and it uses the smaller pieces of fabric I already own instead of having to buy a big piece of new fabric.